Biochemistry, biophysics, bioinformatics
Functional assignment of uncharacterised enzymes
Prof. Dr. Patrick Babinger
- Important information: We are interested in the characterisation of previously unknown enzymes, especially those in the context of ether lipid biosynthesis, and of enzymes that can bind nucleic acids in addition to their catalytic activity.
Mass spectrometry
Dr. Astrid Bruckmann
- Important information: Our group aims at providing state-of-the-art mass spectrometric methods which are tailored to the project specific requirements of our collaboration partners within the RCB and beyond. We are particularly focusing our interest on quantitative proteomics, interactomics (RNA-and protein proximity labeling workflows), cross-link (XL)-MS methods, analysis of post-translational modifications as well as nascent proteomics.
Further info of Dr. Astrid Bruckmann
Prof. Dr. Neva Caliskan
- Important information: Neva Caliskan's research group investigates the role of RNA molecules in non-canonical translation events that can influence the interaction between host and pathogen. Their goal is to shed light on therapeutic RNA-protein complexes as new targets in the fight against infections.
Further info of Prof. Dr. Neva Caliskan
Reproduction, stem cells and stress
Prof. Dr. Thomas Dresselhaus
- Important information: We are studying gene regulatory networks during plant germline and seed development, fertilization mechanisms, also under environmental stress.
Further info of Prof. Dr. Thomas Dresselhaus
Structural biochemistry
Prof. Dr. Christoph Engel
- Important information: Structural biochemistry
We use structural Biology tools, such as cryo-Electron Microscopy and X-ray crystallography to elucidate ribonuclear-protein complex structures at atomic resolution. This allows us to study the molecular basis of transcription by eukaryotic RNA-polymerases.
Further info of Prof. Dr. Christoph Engel
Chromatin, gene expression and development
Prof. Dr. Klaus Grasser
- Important information: We study how RNAPII transcript elongation and co-transcriptional processes in the chromatin context impact development and stress responses in plants
Further info of Prof. Dr. Klaus Grasser
Prof. Dr. Joachim Griesenbeck
- Important information: Durch unsere Forschung versuchen wir Chromatinstruktur und Regulation der Transkription eukaroytischer Gene besser zu verstehen.
Further info of Prof. Dr. Joachim Griesenbeck
Engineering of light control in enzymes
PD Dr. AG Hupfeld
- E-mail address: andrea.hupfeld(at)ur.de (opens your email program)
- Tel: +49-941-943 7439 (starts a telephone call, if your device allows this)
- Location: Westliche Naturwissenschaften, E3_1.315
- Important information: Our goal is the develpment, investigation and application of enzymnatic photocontrol using unnatural amino acids.
RNA transport in plants
Prof. Dr. Aline Koch
- Important information: We study how regulatory non-coding and coding RNAs can be used as "sprayable RNAs" to improve the agricultural value of crops
Further info of Prof. Dr. Aline Koch
NMR spectroscopy under high hydrostatic pressure
Prof. Dr. Werner Kremer
- Important information: NMR spectroscopy of Biomolecules under High Hydrostatic Pressure
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Chromatin dynamics and nuclear architecture
Prof. Dr. Gernot L?ngst
- Important information: The packaging of eukaryotic DNA into chromatin presents an overriding regulatory layer to all DNA dependent processes, like transcription or replication.
Further info of Prof. Dr. Gernot L?ngst
Male flower development
PD Dr. Karina van der Linde
- Important information: We focus on the molecular aspects of maize yield, with a particular emphasis on agriculturally relevant questions of plant developmental biology and plant-pathogen interactions plus their points of overlap. In recent years, we also started to investigate the impact of climate change on maize yield. To enable groundbreaking research on maize, which is not a typical laboratory model plant but the world's most grown staple crop, our research always also aims at establishing novel methods specifically tailored to maize.
Further info of PD Dr. Karina van der Linde
Gene regulation through microRNAs
Prof. Dr. Gunter Meister
- Important information: Cellular Biochemistry and Biophysics
Further info of Prof. Dr. Gunter Meister
RNP Granules
Dr. Nina Ripin
- Important information: We use interdisciplinary strategies to investigate the properties, biological functions, and disease relevance of stress-induced ribonucleoprotein (RNP) granules. Our research focuses on the role of RNA and its interactions with RNA chaperones—such as DEAD-box helicases and RNA-modifying enzymes—in shaping the integrated stress response.
Further info of Dr. Nina Ripin
Mechanisms of molecular machines
Prof. Dr. Till Rudack
- Important information: Our goal is to gain cross-scale, time-resolved atomic insights into the structure, dynamics and function of molecular machines with biomedical or biotechnological relevance. To this end, we develop and apply computational strategies that combine different methods from bioinformatics, theoretical biophysics and quantum chemistry.
Circular RNA-mediated plant protection
Dr. Timo Schlemmer
- Important information: Our research focus is dedicated to the development and production of innovative RNA-based crop protection agents based on circular RNAs. Our goal is to develop sustainable alternatives to chemically synthetic pesticides and to bring them to market in the future.
Further info of Dr. Timo Schlemmer
Biomolecular nmr spectroscopy
Prof. Dr. Remco Sprangers
- Important information: The primary scientific goal of our research is to understand the relationship between protein motions and protein function
Further info of Prof. Dr. Remco Sprangers
Enzyme Evolution and Protein Design
Prof. Dr. Reinhard Sterner
- Important information: Our research focuses on enzymes, i.e. complex proteins that catalyze cellular reactions with high specificity and efficiency.
Protein engineering for super-resolution microscopy
Prof. Dr. Andre C. Stiel
- Important information: Imaging is our window into the intricate details of life in health and disease. We develop the molecular tools to advance optical imaging. Driven by curiosity and a passion for colour and light.
Gamete interaction and cell polarity
Prof. Dr. Stefanie Sprunck
- Important information: We are working on flowering plant gamete formation, male-female gamete interactions and the establishment of cell polarity.
Further info of Prof. Dr. Stefanie Sprunck
Ubiquitin-dependent cell signalling
Dr. Silke Wiesner
- Important information: Ubiquitin-dependent Cell Signaling
Further info of Dr. Silke Wiesner
Structure and function of membrane proteins
Prof. Dr. Christine Ziegler
- Important information: Structure and function of membrane proteins